At the end of your morning and evening skincare routine, take a small pearl-sized amount onto your fingertips and gently apply to areas with wrinkles, such as around the eyes and mouth. *If using in the morning, to protect the effectiveness of the retinol, apply UV-blocking cosmetics after use. <How to open> (1) Open the cap and discard the blue ring. (2) Place the cap straight onto the tube container and screw it in until the uneven base is no longer visible. (3) Remove the cap to reveal the inner stopper. (Precautions for Use) .Discontinue use if any skin irritation occurs after exposure to direct sunlight. .Avoid contact with eyes. .After use, wipe the opening of the tube container thoroughly and close the cap tightly. .Do not pull up the base of the inner stopper unless replacing the tube. .Do not store in direct sunlight or in hot, humid places. .Keep out of reach of children. .Refills (sold separately) are available. When purchasing refills (sold separately), do not discard the cap or inner stopper. *Please refrain from using this product if you have previously experienced problems with products containing retinol or if you are prone to skin irritation. *When using this product for the first time or if your skin is sensitive, we recommend gradually increasing the amount used, using it only at night every 2-3 days for the first 2 weeks, and then every night for the next 2 weeks. *When using this product in combination with other retinol-containing products, avoid using multiple products at once. Use each product individually, monitoring the results. *Please use correctly, observing the recommended number of uses and dosage. *If using this product on the neck for the first time, please follow the same precautions as for the face. *If you have previously experienced problems on your face, please refrain from using this product on your neck. *If problems occur, discontinue use on that area (face and neck).