POLA
Pola Wrinkle Shot Medical Serum Grand Size, 30g
Pola Wrinkle Shot Medical Serum Grand Size, 30g
@cosme rating: 5.2/7.0
1.5 times the size of Wrinkle Shot Medical Serum N
✓ 100% authentic
✓ Ships from Japan in 3-5 days
✓ Duties prepaid for US orders
✓ Tracked delivery via Japan Post
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What it is
Product Name: POLA Wrinkle Shot Medical Serum N .Quasi-drug .Allergy tested (not guaranteed to be allergy-free for all users) Contains "NEI-L1(R)", a unique ingredient from the POLA-ORBIS Group, which was the first quasi-drug active ingredient in Japan to be recognized for wrinkle improvement. A new Dynamic Delivery formula has also been adopted, allowing the active ingredient NEI-L1* to penetrate deep into the dermis to improve wrinkles. Use approximately 6 months for one area, or approximately 3 months for two areas. * NEI-L1: Sodium trifluoride isopropyl oxopropylaminocarbonylpyrrolidinecarbonylmethylpropylaminocarbonylbenzoylaminoacetate. Since its launch in 2017 as Japan's first*1 wrinkle-improving medicated cosmetic, Wrinkle Shot has been experienced by approximately 1.75 million*2 customers. Even after its launch, we have continued our wrinkle research as a pioneer in wrinkle improvement. By accurately identifying one of the causes of wrinkles, the active ingredient NEI-L1*3 penetrates deep into the dermis to improve them. . Causes of Wrinkles Wrinkles are mainly caused by the excessive production of enzymes (such as neutrophil elastase) that break down dermal components due to ultraviolet rays and facial pressure, damaging the skin. . Mechanism for Improving Wrinkles*4 The wrinkle-improving active ingredient "NEI-L1" suppresses the action of neutrophil elastase and inhibits the breakdown of dermal components in wrinkled areas, thereby supporting the production of dermal components and promoting wrinkle improvement. *1 First in Japan: The first product approved in July 2016 as a quasi-drug for improving wrinkles. *2 Approximately 1.75 million people: Sales performance from January 2017 to the end of March 2024 (according to POLA). *3 NIE-L1: Sodium trifluoride isopropyl oxopropylaminocarbonylpyrrolidinecarbonylmethylpropylaminocarbonylbenzoylaminoacetate. *4 Improves wrinkles: Significant results were obtained in the evaluation criteria of the anti-wrinkle product evaluation guidelines for obtaining new efficacy established by the Japanese Society of Cosmetic Scientists.
Ingredients
Sodium trifluoride isopropyl oxopropylaminocarbonylpyrrolidinecarbonylmethylpropylaminocarbonylbenzoylaminoacetate Other Dimethicone, petrolatum, cross-linked dimethicone, methacrylate resin powder, glyceryl triethylhexanoate, sericite, cyclopentasiloxane, trimethylsiloxysilicate, hydrogenated polybutene, cyclohexylglycerin, squalane, oil-soluble arnica extract, oil-soluble chamomile extract, oil-soluble peach leaf extract, royal jelly extract, thyme extract-1, horsetail extract, hydroxyapatite, phytosteryl/octyldodecyl lauroyl glutamate, liquid paraffin, light isoparaffin, caprylic/capric triglyceride, BG, water, anhydrous silicic acid, zinc oxide, fragrance
How to use
Recommended amount to use: About the size of two grains of rice. *Due to the characteristics of the formula, the texture may change slightly depending on storage conditions such as temperature, but there is no problem with the quality. *Rarely, a clear liquid (part of the ingredients) may come out, but there is no problem with use. How to use: 1. Use after preparing your skin with lotion during your daily morning and evening skincare routine. 2. Take an appropriate amount of serum on your fingertips and apply it to the areas where you are concerned about wrinkles. *For each area (wrinkles around both eyes, around both mouths, forehead, etc.), about the size of two grains of rice is a guideline for the amount to use. 3. Gently apply in the direction of the arrow as if stretching the wrinkles. Stretch from the inside out and from bottom to top. For the eye area (eyelids and under the eyes), gently apply from the inner corner to the outer corner of the eye. Recommended way to use for existing wrinkles and forehead: 1. Gently touch the slanted tip of the tube to your skin. 2. Place the serum along the wrinkles. 3. Gently stretch the product in the direction of the arrow with your fingertips, as if stretching out wrinkles. Precautions for use: Due to the characteristics of the formula, the texture may change slightly depending on storage conditions such as temperature, but this does not affect the quality. Twist the cap to open. Do not press the tip of the tube firmly against your skin. Do not rub your skin vigorously with the tip of the tube. Wipe the tip of the tube after use. Occasionally, a clear liquid (part of the ingredients) may come out, but this does not affect the use of the product. Occasionally, the contents may come out forcefully, so please be careful. If the contents become difficult to dispense, gather the contents towards the tip of the tube before use.
We ship internationally from Japan!
Frequently Asked Questions
Is this authentic?
Yes. We only buy from official retailers and directly from the brands here in Japan. Never resellers, never grey market stock.
We are beauty lovers too, so we know the worry, especially with something you are putting on your face. Authenticity is 100% guaranteed by us.
What are your shipping rates?
On orders under US$75, shipping is a flat US$20 to the United States and US$10 to all other countries.
Orders of US$75 or more ship free, applied automatically at checkout. Your exact shipping cost is shown before you pay.
How long does delivery take?
These estimates are for International Airmail (Tracked) and include 3 to 5 business days of processing in Japan.
- United States: 12 to 15 business days
- Canada, United Kingdom, France, Germany: 9 to 12 business days
- Australia, New Zealand, Denmark, Finland, India, Indonesia, Italy, Netherlands, Spain, Sweden, Switzerland: 10 to 13 business days
- China, Hong Kong, Malaysia, Singapore, South Korea, Taiwan, Thailand, Vietnam: 8 to 10 business days
- Rest of the world: 11 to 18 business days
Actual delivery can be affected by customs clearance, seasonal congestion, or carrier delays in the destination country, all of which are outside our control.
Do you offer express shipping?
Yes. As of 22 July 2026, we offer International Express Mail through Japan Post. The cost is based on order weight and is calculated automatically at checkout.
Will I pay customs or import fees?
US orders: No. As of July 1, 2026, all US orders ship DDP (duties delivered prepaid), meaning we prepay all import duties on our end. Nothing is due at your door.
Orders outside the US: Possibly. Duties and import taxes are set by your local customs authority and are not collected at checkout, so any charges on delivery are your responsibility.
We're working on rolling out prepaid duties for more countries soon.