Humanano
Humanano Placenta Extract Grande, 100ml
Humanano Placenta Extract Grande, 100ml
@cosme rating: 5.0/7.0
Serious anti-aging care with human placenta extract containing 75,000 times the growth factors
✓ 100% authentic
✓ Ships from Japan in 3-5 days
✓ Duties prepaid for US orders
✓ Tracked delivery via Japan Post
Couldn't load pickup availability
What it is
Placenta is an ingredient extracted from the placenta that contains many growth factors that support the skin and is effective against skin aging. Placenta concentrate is the first in Japan to contain bio-human ingredients with the same genetic structure as the growth factors in human placenta. What's more, it's a free-form formula, so it can be used safely even by those with sensitive skin. . Contains human placenta and five major bio-human ingredients that support the skin (EGF, IGF, aFGF, TRX) . 100% nano-sized for high penetration into the skin and quick absorption. . No animal-derived ingredients, mineral oil, parabens, fragrances, pigments, silicone, surfactants, or alcohol
Ingredients
Water, human oligopeptide-1, synthetic human recombinant polypeptide-31, human oligopeptide-13, synthetic human recombinant polypeptide-16, human oligopeptide-4, lecithin, soybean oil, glycerin, phenoxyethanol, tocopherol acetate
How to use
After washing your face, apply it all over your face. Then, condition your skin with lotion and cream.
We ship internationally from Japan!
Frequently Asked Questions
Is this authentic?
Yes. We only buy from official retailers and directly from the brands here in Japan. Never resellers, never grey market stock.
We are beauty lovers too, so we know the worry, especially with something you are putting on your face. Authenticity is 100% guaranteed by us.
What are your shipping rates?
On orders under US$75, shipping is a flat US$20 to the United States and US$10 to all other countries.
Orders of US$75 or more ship free, applied automatically at checkout. Your exact shipping cost is shown before you pay.
How long does delivery take?
These estimates are for International Airmail (Tracked) and include 3 to 5 business days of processing in Japan.
- United States: 12 to 15 business days
- Canada, United Kingdom, France, Germany: 9 to 12 business days
- Australia, New Zealand, Denmark, Finland, India, Indonesia, Italy, Netherlands, Spain, Sweden, Switzerland: 10 to 13 business days
- China, Hong Kong, Malaysia, Singapore, South Korea, Taiwan, Thailand, Vietnam: 8 to 10 business days
- Rest of the world: 11 to 18 business days
Actual delivery can be affected by customs clearance, seasonal congestion, or carrier delays in the destination country, all of which are outside our control.
Do you offer express shipping?
Yes. As of 22 July 2026, we offer International Express Mail through Japan Post. The cost is based on order weight and is calculated automatically at checkout.
Will I pay customs or import fees?
US orders: No. As of July 1, 2026, all US orders ship DDP (duties delivered prepaid), meaning we prepay all import duties on our end. Nothing is due at your door.
Orders outside the US: Possibly. Duties and import taxes are set by your local customs authority and are not collected at checkout, so any charges on delivery are your responsibility.
We're working on rolling out prepaid duties for more countries soon.
I bought a trial size of the placenta extract lotion. It's 8ml and has a slightly fishy smell that's unique to placenta. It's a watery lotion with a light texture. I haven't used it when my skin was feeling unwell, so I can't say for sure, but it didn't feel like it tightened my skin. It did, however, feel like the fine hairs on the surface of my skin were smooth, like they'd been dusted with powder... I think it's a mild lotion.
I regularly purchase this product because of its appealing ingredients. While many products list water, BG, pentylene glycol, and ethanol at the top of their ingredients list, I was attracted to this product because it lists peptide ingredients after water. I primarily use it as a booster immediately after washing my face. It's odorless, so even those sensitive to scents can use it. I was surprised at how smooth it felt when I first started using it. It blends in smoothly and is absorbed naturally into my skin. I couldn't help but glance at the box, wondering if it contained ethanol in the top ingredients. It's not sticky, so it doesn't interfere with the serum or cream I use afterwards. While it doesn't have an immediate effect, I believe it's the reason I'm still free of serious blemishes and wrinkles, and I'm continuing to use it. Plus, the price is reasonable considering the ingredients. It's a reliable skin watchdog.
Humanano Placenta Extract has a smooth texture that is easily absorbed into the skin, leaving it non-sticky and leaving it feeling moisturized and supple even the next morning. The dropper design makes it easy to adjust the amount, and the safe ingredients make it hypoallergenic, allowing you to enjoy anti-aging care without any hassle. Another appealing feature is that you can gradually feel the firmness and clarity of your skin. While it lacks the fishy smell and immediate effects typical of placenta, and its effects are difficult to detect, it is easy to incorporate into your daily skincare routine, and the longer you use it, the better your skin will look. We recommend it.
I bought the trial version to treat wrinkles and sagging skin. It's a smooth liquid, and I didn't mind the smell at all. I use it as an introduction to the beauty salon before applying lotion. I've been using it for a few days, and it feels like my skin is becoming more moisturized. I think I need to use it for a while longer to treat wrinkles and sagging skin, so I'll wait and see how it goes.