Hepatreat Medicated Anti-Aging Serum, 45ml

Hepatreat is a skincare brand with a hypoallergenic formula based on heparinoids, enveloping and protecting the skin like a "moisture veil." Its active ingredient is dipotassium glycyrrhizinate, which addresses not only dryness but also skin conditions prone to roughness. ♪ Moisturizing without stickiness: It absorbs into the skin, leaving it comfortable and without a heavy feeling. ♪ The peace of mind of knowing your skin is well-hydrated: Even in dry seasons, your skin will feel less "tight." ♪ Lightweight to use: It's easy to use as a cotton pack, and doesn't feel heavy even when layered. Because it's highly moisturizing, I plan to use it more actively as my skin gets drier.

On September 16, 2025, Welcia had a sale on this set with a mini lotion, so I bought it to try. This is the old packaging. Release date: September 6, 2024 (additional release date: July 25, 2025). It's a gel-type serum, so I use it after applying lotion. The retail price seems to be 1,980 yen for 45ml, the same price as a 380ml lotion and a 230g emulsion, so it feels a little pricey. However, it's a quasi-drug, transparent, refreshing gel that spreads easily across the face with one pump, leaving it non-sticky and irritating, even during the hot and humid weather. I used it before bed, and my skin was still moisturized when I woke up. I can't tell if it will improve wrinkles in the short term, but I'll check to see if it's comfortable to use during the hay fever season in the fall. … … …From the description: Renewed packaging. Pre-release date: September 3, 2025, available at Suzykirei TOKYO. This medicated anti-aging serum aims to fundamentally resolve skin concerns. Its refreshing texture melts into the skin, leaving it plump, firm, and lifted. Formulated with two active ingredients, the moisturizing active ingredient "heparinoid" and the skin-irritating active ingredient "dipotassium glycyrrhizinate," it addresses a variety of skin concerns, including dryness, roughness, texture, pores, and acne. This renewed product adds moisturizing ingredients (three types of ceramides*1 and three types of amino acids*2) to the existing product. Hypoallergenic formula (fragrance-free, colorant-free, mineral oil-free, animal oil-free, paraben-free, alcohol-free, silicone-free) *1 N-stearoyl dihydrosphingosine, N-stearoyl phytosphingosine, hydroxystearyl phytosphingosine *2 L-histidine, glycine, L-glutamic acid

I tried Hepatreat serum. It contains the moisturizing active ingredient "heparinoid" and the skin-irritating active ingredient "dipotassium glycyrrhizinate," as well as "niacinamide," which reduces the appearance of fine lines caused by dryness. The texture is a clear, soft, and thick gel that spreads easily and blends seamlessly into the skin without feeling sticky. After toning my skin with lotion, I spread it all over my face with one pump and blend it in. I especially worry about dryness around my mouth and eyes, so I apply it multiple times. The pollen allergy is making my eyes especially itchy and sensitive, but this serum doesn't sting and I can use it without worry. Its hypoallergenic formula makes it ideal for times when dryness and rough skin are a concern. It also contains collagen peptides and niacinamide, which are appealing. It's easily available at drugstores, offers good value, and is easy to repurchase. I highly recommend it for those struggling with dry skin or rough skin during sensitive periods.

It was incredibly popular and sold out at Loft... This medicated anti-aging serum for sensitive skin is a powerful combination of moisturizing active ingredients, heparinoids, and skin-irritating active ingredient dipotassium glycyrrhizinate. It also contains three types of ceramides and amino acids, as well as niacinamide and penetrating and adhesive collagen peptides. Its refreshing, light texture melts into your skin, and when gently applied to areas with signs of aging, such as around the eyes, corners of the eyes, and nasolabial folds, it leaves your skin plump, firm, and radiant. Despite its refreshing texture, it also provides excellent moisturizing and hydrating properties. It's fragrance-free, colorant-free, alcohol-free, mineral oil-free, animal oil-free, paraben-free, and silicone-free, making it gentle enough for daily use and a reliable choice for sensitive skin.

Recently, I've been worried about my skin's lack of vitality, but since I started using this, it's been great! Even though it's a thick serum, it absorbs smoothly into the skin without leaving a sticky feeling. After use, my skin feels plump and moisturized. I liked the feeling of it gently enveloping the areas around my eyes and mouth, where I'm concerned about fine lines and dryness. The fact that it's medicated is also a relief. ◎ It's gentle and easy to use both in the morning and at night, so it's great for those who are concerned about dryness and want firmness, or who want to start anti-aging care. This serum is just right for those who want to gently incorporate it into their daily skincare routine.