BIOHITO
Biohito Bio Human Serum, 30ml
Biohito Bio Human Serum, 30ml
@cosme rating: /7.0
Cutting-edge skincare focused on human stem cells and exosomes
✓ 100% authentic
✓ Ships from Japan in 3-5 days
✓ Duties prepaid for US orders
✓ Tracked delivery via Japan Post
Couldn't load pickup availability
What it is
This serum is packed with essential ingredients for mature skin, including the popular 2021 ingredient "retinoid" and the noteworthy ingredient "functional peptide." It contains:. Human stem cell culture fluid with exosomes. Firming peptides (Argireline, Matrixyl, Syn-Ake). Retinol palmitate (vitamin A derivative). Vitamin C3 (pure vitamin C, water-soluble vitamin C, oil-soluble vitamin C derivative). Moisturizing ingredients (two types of ceramides and 10 types of plant extracts). This serum contains 10% human stem cell culture fluid (liposomes), rich in over 100 growth factors, including exosomes, EGF, FGF, and IFG, which enhance skin's firmness and radiance. It also contains a luxurious blend of highly functional peptides, including Argireline (c), Syn-Ake (c), Matrixyl (c), retinol palmitate (vitamin A derivative), vitamin C3 (pure vitamin C, water-soluble vitamin C, oil-soluble vitamin C derivative), fullerene, and moisturizing ingredients, all of which are beneficial for mature skin. <Expected effects>. Tightens sagging skin around the cheeks and eyes, and fine lines. Improves skin texture for firmer skin. Makes makeup go on much better the next day. Leaves skin with a translucent appearance. Strengthens the skin's barrier function for less roughness
Ingredients
Water, Butylene Glycol, Glycerin, Pentylene Glycol, Human Stem Cell Conditioned Media, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Ascorbyl Tetrahexyldecanoate, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Ascorbic Acid, Alanine, Isoleucine, Glycine, Glutamic Acid, Serine, Tyrosine, Threonine, Valine, Histidine HCl, Phenylalanine, Proline, Lysine HCl, Leucine, Taurine, Sodium Aspartate, Allantoin, Arginine, Disodium Inosinate, Disodium Guanylate, Fullerenes, Alpha-Arbutin, Retinol Palmitate, Magnesium Ascorbyl Phosphate, Panthenol, Tocopherol, Tocopherol Acetate ethanol, ceramide NP, sodium hyaluronate, water-soluble proteoglycan, rosemary leaf extract, chamomile flower extract, aloe vera leaf extract, pomegranate peel extract, morus alba root bark extract, ginkgo biloba leaf extract, scutellaria root extract, saxifrage extract, paeonia suffruticosa root extract, pueraria lobata root extract, caprylic/capric triglyceride, zea mays (corn) oil, squalane, hydrogenated lecithin, dipotassium glycyrrhizinate, water-soluble collagen, xanthan gum, carbomer, hydroxyethylcellulose, citric acid, sodium citrate, PVP, polysorbate 80, polysorbate 20, PEG-60 hydrogenated castor oil, disodium EDTA, caprylyl glycol, 1,2-hexanediol, phenoxyethanol
How to use
Shake well before use. It has a light texture and penetrates easily, so you can use it as an "introductory serum" immediately after washing your face, or as a "treatment serum" immediately after applying lotion, whichever you prefer. As you massage it into your skin and press it in, you will feel your skin become plumper and more supple. The effect lasts for 12 hours, so using it twice a day, morning and night, will ensure 24-hour results.
We ship internationally from Japan!
Frequently Asked Questions
Is this authentic?
Yes. We only buy from official retailers and directly from the brands here in Japan. Never resellers, never grey market stock.
We are beauty lovers too, so we know the worry, especially with something you are putting on your face. Authenticity is 100% guaranteed by us.
What are your shipping rates?
On orders under US$75, shipping is a flat US$20 to the United States and US$10 to all other countries.
Orders of US$75 or more ship free, applied automatically at checkout. Your exact shipping cost is shown before you pay.
How long does delivery take?
These estimates are for International Airmail (Tracked) and include 3 to 5 business days of processing in Japan.
- United States: 12 to 15 business days
- Canada, United Kingdom, France, Germany: 9 to 12 business days
- Australia, New Zealand, Denmark, Finland, India, Indonesia, Italy, Netherlands, Spain, Sweden, Switzerland: 10 to 13 business days
- China, Hong Kong, Malaysia, Singapore, South Korea, Taiwan, Thailand, Vietnam: 8 to 10 business days
- Rest of the world: 11 to 18 business days
Actual delivery can be affected by customs clearance, seasonal congestion, or carrier delays in the destination country, all of which are outside our control.
Do you offer express shipping?
Yes. As of 22 July 2026, we offer International Express Mail through Japan Post. The cost is based on order weight and is calculated automatically at checkout.
Will I pay customs or import fees?
US orders: No. As of July 1, 2026, all US orders ship DDP (duties delivered prepaid), meaning we prepay all import duties on our end. Nothing is due at your door.
Orders outside the US: Possibly. Duties and import taxes are set by your local customs authority and are not collected at checkout, so any charges on delivery are your responsibility.
We're working on rolling out prepaid duties for more countries soon.
I received a sample and tried it out. One sample packet contains enough for about three uses, and when I picked it up, it was odorless and had a smooth texture. I think I'll be able to use it without any hesitation. It's smooth to use, and naturally moisturizes my skin. My skin felt good the next day. I feel like my skin is softer.
My skin became soft and supple after using it! It was also easy to use as an introductory serum!
If you use it at night, you can feel the effects the next morning. It has a thick texture that is great for dry skin. I'm glad I found it when I started to worry about aging.
I received a sample. I haven't been using it regularly so I don't know if it's effective, but it felt great to use.