Wrinkle Shot Medical Serum N, 20g

Sales name: POLA Wrinkle Shot Medical Serum N, quasi-drug, allergy tested (does not mean that allergies will not occur in all people) Contains POLA ORBIS Group's original ingredient "Nil One R", which was recognized as the first quasi-drug active ingredient to improve wrinkles in Japan. It also adopts a new dynamic delivery formula, and the active ingredient Neil One * penetrates deep into the dermis of the skin to improve wrinkles. Please use it for about 4 months for one area and about 2 months for two areas. * Neil One: Trifluoroisopropyl oxopropyl aminocarbonyl pyrrolidine carbonyl methylpropyl aminocarbonyl benzoyl aminoacetate Na Since its launch in 2017 as Japan's first * 1 wrinkle-improving medicated cosmetic, Wrinkle Shot has been experienced by about 1.75 million * 2 customers. Even after its launch, we have continued wrinkle research as a pioneer in wrinkle improvement. By accurately identifying one of the causes of wrinkles, the active ingredient Neil One * 3 penetrates deep into the dermis of the skin and improves it. . Cause of wrinkles Wrinkles are mainly caused by ultraviolet rays and facial pressure, which cause excessive production of enzymes (such as neutrophil elastase) that break down dermal components, damaging the skin. . How it improves wrinkles*4 The active ingredient for improving wrinkles, "Nilone," suppresses the activity of neutrophil elastase and inhibits the breakdown of dermal components in wrinkled areas, thereby supporting the production of dermal components and promoting the improvement of wrinkles. *1 First in Japan: A product first approved in July 2016 as a quasi-drug for improving wrinkles*2 Approximately 1.75 million people: Sales record from January 2017 to the end of March 2024 (according to POLA)*3 Nilone: ​​Trifluoroisopropyloxopropylaminocarbonylpyrrolidinecarbonylmethylpropylaminocarbonylbenzoylaminoacetate Na*4 Improves wrinkles: Significance was obtained in the evaluation criteria of the anti-wrinkle product evaluation guidelines for obtaining new efficacy established by the Japan Cosmetic Science Society. (Quasi-drug)

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Active ingredients: Trifluoroisopropyl oxopropyl aminocarbonyl pyrrolidine carbonyl methylpropyl aminocarbonyl benzoyl aminoacetate sodium Other ingredients: Dimethicone, petrolatum, crosslinked dimethicone, methacrylic acid ester resin powder, triethylhexanoate glyceryl, sericite, cyclopentasiloxane, trimethylsiloxysilicate, hydrogenated polybutene, cyclohexylglycerin, squalane, oil-soluble arnica extract, oil-soluble chamomilla extract, oil-soluble peach leaf extract, royal jelly extract, thyme extract-1, horsetail extract, hydroxyapatite, di(phytosteryl-octyldodecyl) lauroyl glutamate, liquid paraffin, light isoparaffin, tri(capryl-capric acid)glyceryl, BG, water, anhydrous silicic acid, zinc oxide, fragrance